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BEDMINSTER, N.J., Feb. 25, 2021 /PRNewswire/ Jubilant Therapeutics Inc., a biopharmaceutical company advancing small molecule modulators to address unmet medical needs in oncology and autoimmune diseases, today announced a collaboration with Boston Children s Hospital (https://wistar.org/) to evaluate peptidyl arginine deiminase 4 (PAD4) inhibitors under development by Jubilant Therapeutics to explore the modulation of neutrophil extracellular traps (NETosis) in preclinical models of neutrophil regulation and rheumatoid arthritis (RA).
PAD4 is an enzyme that converts arginine to citrulline in histones and is highly expressed in neutrophils. Histone citrullination has been implicated in the formation of NETs which is believed to contribute to pro-inflammation and disease progression in many autoimmune disorders including RA, fibrosis, lupus and ARDS.
Coronaviruses donât just impact humans. As one cat owner learned, they can affect pets, too. As the pandemic continues, much has been revealed about coronaviruses â a family of viruses that includes the one that causes COVID-19. (Source: Daniela Stolfi-Tow) By Mark Carpenter | February 24, 2021 at 6:56 PM HST - Updated February 25 at 1:54 PM
HONOLULU, Hawaii (HawaiiNewsNow) - As the pandemic continues, much has been revealed about coronaviruses â a family of viruses that includes the one that causes COVID-19.
For one thing, the viruses donât just impact humans. They can get animals sick, too.
Kailua resident Daniela Stolfi-Tow recently learned that after adopting a short-haired cat named Naya.
The International Medieval Congress (IMC), one of the biggest academic conferences taking place online in the world this year, is to take climates as its.
Published February 23. 2021 7:41PM
Kelan Lyons, The Connecticut Mirror
Three weeks into the Department of Correction’s vaccinations of the incarcerated population, 837 inmates less than 10% of the 9,034 people in prisons and jails as of Feb. 22 have received the first dose of the COVID-19 vaccine.
The department received another 500 doses Tuesday morning. Department Director of External Affairs Karen Martucci said the DOC has used all of the shots it has received and is seeking more.
“We roll them out as they come in,” she said.
The DOC began vaccinating the 27 incarcerated individuals age 75 or older in early February and then began vaccinating people between the ages of 65 and 74.